Recruiting at all levels!

We are broadly interested in exceptionally driven individuals with background and/or interests in genome regulation, synthetic biology, combinatorial genetics, quantitative biology, computational biology, cell differentiation control, tissue injury responses (regeneration and/or fibrosis), and immune recognition of cancer cells. We are excited about both technology development and fundamental biology.

We value strong work ethic, enthusiasm, creativity, rigor, and affinity for collaborations.

We strive to create a supportive environment where individuals are encouraged to grow together scientifically and professionally by challenging ideas, each other, and themselves.

Prospective graduate students:

Instructions for UCSF graduate students considering a rotation: Please contact Chris with your CV, a statement of your interest in the lab, and potential start and end dates of rotation. Please do so as early as possible to express your interest in rotating, preferably 2 or more months ahead of the start of your potential rotation so that there would be sufficient time for Chris to meet with you over several sessions to explore scientific interests and fit prior to the start of the rotation. I am happy to discuss the potential for co-mentorships, where appropriate, such as for students with interests in computation or specific biological domains in tissue biology.

Prospective postdocs and physician-scientists:

Please see additional descriptions in the job posting. Currently we are especially interested in individuals at the post-doctoral level with a background in genome regulation and liver biology, including those with experience working with in vivo models. I am happy to discuss potential formal or informal co-mentorship arrangements that may strengthen your career development, if appropriate. We collaborate extensively with other labs in the Liver Center, Institute for Regenerative Medicine, and immuno-oncology community at UCSF. Where appropriate, outstanding candidates will be considered for opportunities to work collaboratively with help from junior specialists.

Please contact Chris with your CV, a statement of your interest in the lab, potential start date, and contact information for 2-3 references.

Prospective junior specialists:

We are looking to recruit a highly motivated individual who has prior experience/skills at the bench in a molecular biology laboratory setting. This is a unique opportunity most suitable for a soon-to-graduate senior to gain full-time experience (minimum 2-year commitment) in developing and/or applying cutting-edge CRISPR synthetic biology and functional genomics approaches to topics with therapeutic relevance. Interest in working with mice is desirable. Some possible projects include:

• Discovering perturbations to cancer cells to elicit systemic anti-tumor immunity using novel CRISPR screening approaches in mouse models

• Applying high-throughput approaches to study tissue injury responses, such as regeneration or fibrosis, including in new models of cultured mouse or human tissues and in mouse models.

• Developing new CRISPR tools to manipulate transcriptional control for discovery science and therapeutics

The expectation is a highly independent and driven individual with the ability to contribute to projects creatively, as well as routine tasks for laboratory upkeep and inventory maintenance. Interested individuals will receive relevant career mentorship, including MD and/or PhD career paths.

If interested, please directly email Chris (even if you have already applied through a UCSF job posting page) one pdf attachment that includes your CV and the following information:

1. Why are you interested in the lab?

2. Are you planning to apply to graduate/professional school within the next 3 years? If so, what type of program are you considering and when do you plan to apply?

3. What are the earliest and latest dates you can start?

4. Please provide the contact information for 1-3 references and indicate their professional relationship to you. We are looking for people who would be willing to speak to us about their experience working with you in your previous research and/or job positions.

5. Please provide your undergraduate transcript.